Grape seed extract, extracted from the seeds of grapes, is rich in antioxidants and is valued for its many health benefits. The extract is particularly well-known for its positive effects on the cardiovascular system, skin health, and protection of cells from oxidative stress. Grape seed extract has become increasingly popular in recent years because it offers a natural source of powerful antioxidants that can promote general well-being. In this article, you will learn everything you need to know about grape seed extract, its health benefits, and how to use it safely.

What is grape seed extract?

Grape seed extract is derived from the seeds of wine grapes ( Vitis vinifera ) and is particularly rich in polyphenols, including oligomeric proanthocyanidin complexes (OPC), which act as powerful antioxidants. These compounds help protect cells from free radical damage and reduce inflammatory processes in the body. Grape seed extract is often used as a dietary supplement to support heart health, slow skin aging, and promote general cell protection [1].

Grape seed extract is derived from the byproducts of wine production, which leaves the seeds of grapes. These seeds are dried and processed to extract the valuable polyphenols. The grapes are usually sourced from wine-growing regions, such as Europe, North America, and South America. Grape seed extract has been a popular dietary supplement for years, especially in natural medicine, due to its potential health benefits [2].

Grape seed extract is obtained from the seeds of grapes using various extraction methods, usually using solvents such as ethanol or water. This extraction process concentrates the polyphenols, especially OPCs, which are the main active ingredients in grape seed extract. The resulting extract is then processed into capsules, tablets or powder and sold as a dietary supplement [3].

Health Benefits of Grape Seed Extract

One of the most well-researched benefits of grape seed extract is its positive effect on heart health. Studies show that the extract can help lower blood pressure, improve circulation, and regulate cholesterol levels. The OPCs contained in grape seeds have a vasodilatory effect and improve the elasticity of blood vessels, which can reduce the risk of cardiovascular disease [4]. In addition, grape seed extract can reduce the risk of atherosclerosis by preventing the buildup of plaque in the arteries.

Grape seed extract is an exceptionally rich source of antioxidants that protect the body from the damaging effects of free radicals. These free radicals are created by environmental factors such as air pollution, smoking and stress and can cause cellular damage that leads to chronic diseases and premature aging. The polyphenols in grape seed extract neutralize these free radicals, helping to protect cells and maintain health [5].

Another benefit of grape seed extract is its positive effect on skin health. The antioxidant properties of the extract help protect the skin from UV damage and reduce the signs of aging such as wrinkles and dark spots. Studies show that grape seed extract can promote collagen production in the skin, thus improving skin elasticity [6]. It is often used in skin care products and supplements to support youthful and radiant skin.

Grape seed extract also has anti-inflammatory properties that can help reduce chronic inflammation in the body. This effect is particularly useful for conditions that involve chronic inflammation, such as arthritis or inflammatory bowel disease. The polyphenols in grape seed extract can reduce the production of pro-inflammatory molecules, thereby reducing pain and swelling [7].

How does grape seed extract work in the body?

Grape seed extract works due to its high levels of antioxidants, especially OPCs, which neutralize free radicals and thus prevent cell damage. These polyphenols support blood vessel health by improving the elasticity of the arteries and reducing the formation of plaques. Grape seed extract also promotes collagen production, which has a positive effect on the skin and connective tissue. In addition, its anti-inflammatory properties help reduce inflammation in the body [8].

Recommended dosage and use of grape seed extract

The recommended dosage of grape seed extract varies depending on the intended use, but is usually between 100 and 300 mg per day. For supporting heart health and general antioxidant protection, a daily dose of 150 to 300 mg is often recommended. It is advisable to start with a lower dose and increase it if necessary to check tolerance [9]. Supplements high in OPCs are particularly effective.

Grape seed extract can be taken at any time of day, ideally with a meal to improve absorption. When taken to support skin health or cardiovascular function, it is advisable to take the extract regularly over a longer period of time for optimal results [10]. There are no specific restrictions on when to take it, but regular intake is crucial for effectiveness.

Side effects and safety of grape seed extract

Grape seed extract is generally considered safe when taken in recommended dosages. In clinical studies, grape seed extract was well tolerated without showing any serious side effects. However, it is advisable to consult a doctor before taking any new supplement, especially if you have existing health problems or are taking medications [11].

Possible side effects of grape seed extract include mild gastrointestinal discomfort such as nausea or digestive problems, especially at higher doses. In rare cases, headaches may also occur. People taking blood-thinning medications should be careful, as grape seed extract can affect blood clotting [12].

Grape seed extract compared to other ingredients

Both grape seed extract and vitamin C are powerful antioxidants that protect the body from oxidative stress. While vitamin C acts directly as a free radical scavenger and supports the immune system, the polyphenols in grape seed extract provide additional benefits for cardiovascular health and skin. Both substances can work synergistically to maximize antioxidant protection and promote overall health [13].

Resveratrol is another polyphenol commonly found in grapes and red wine that is known for its heart-protective properties. While resveratrol offers similar antioxidant benefits as grape seed extract, grape seed extract focuses more on supporting blood vessels and skin health. Both compounds can be used together to provide more comprehensive health benefits [14].

Sources of grape seed extract

Grape seed extract is obtained from the seeds of grapes that are left over from wine production. The seeds of red and purple grapes in particular are rich in polyphenols and OPCs. These ingredients are only present in small amounts in the grapes themselves, which is why the extract from the seeds is considered a concentrated source of antioxidants. Other foods that contain similar antioxidants are berries, nuts and green tea [15].

Final Thoughts on Grape Seed Extract

Grape seed extract is a powerful antioxidant that offers numerous health benefits, including protecting the heart, supporting skin health, and protecting cells from oxidative stress. Whether taken as a capsule, powder, or gummy, grape seed extract is a versatile and effective supplement to promote overall wellness. For people looking to improve their cardiovascular health or combat the signs of aging, grape seed extract is a valuable option.

references

[1] Examine.com. Grape Seed Extract. Available at: https://examine.com/supplements/grape-seed-extract/
[2] WebMD. Grape Seed Extract - Uses and Benefits. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-958/grape-seed
[3] Healthline. Grape Seed Extract: Benefits, Uses, and Side Effects. Available at: https://www.healthline.com/nutrition/grape-seed-extract
[4] Examine.com. Grape Seed Extract and Cardiovascular Health. Available at: https://examine.com/supplements/grape-seed-extract/
[5] Mayo Clinic. Grape Seed Extract and Antioxidant Protection. Available at: https://www.mayoclinic.org/drugs-supplements-grape-seed-extract/art-20362818
[6] National Institutes of Health. Grape Seed Extract for Skin Health. Available at: https://pubmed.ncbi.nlm.nih.gov/15629262/
[7] Examine.com. Grape Seed Extract and Inflammation. Available at: https://examine.com/supplements/grape-seed-extract/
[8] Healthline. Grape Seed Extract Effects on the Body. Available at: https://www.healthline.com/nutrition/grape-seed-extract-effects
[9] Examine.com. Grape Seed Extract Dosage and Usage. Available at: https://examine.com/supplements/grape-seed-extract/
[10] Mayo Clinic. Grape Seed Extract Supplementation Forms. Available at: https://www.mayoclinic.org/drugs-supplements-grape-seed-extract/art-20362818
[11] WebMD. Grape Seed Extract Side Effects and Safety. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-958/grape-seed
[12] Healthline. Side Effects of Grape Seed Extract. Available at: https://www.healthline.com/nutrition/grape-seed-extract-side-effects
[13] Examine.com. Grape Seed Extract vs. Vitamin C. Available at: https://examine.com/supplements/vitamin-c/
[14] Examine.com. Grape Seed Extract vs. Resveratrol. Available at: https://examine.com/supplements/resveratrol/
[15] National Institutes of Health. Natural Sources of Grape Seed Extract. Available at: https://pubmed.ncbi.nlm.nih.gov/15629262/