image
image

Zinc: An essential trace element for the immune system, metabolism and skin

Zinc: An essential trace element for the immune system, metabolism and skin

Zinc is an essential trace mineral that plays a crucial role in many of the body's processes. It is particularly well-known for its ability to boost the immune system, promote wound healing, and support metabolism. Zinc is also important for cell growth, development, and repair. Since the body cannot produce zinc on its own, it must be obtained through food or supplements. In this article, you'll learn about the health benefits of zinc, how it works in the body, and how to use it safely.

What is zinc?

Zinc is an essential trace element found in almost every cell in the body and is involved in more than 300 enzymatic reactions. It is necessary for protein synthesis, cell division, immune system function and maintaining a healthy metabolism. Zinc also plays a role in wound healing and supporting the sense of smell and taste [1].

Synonyms for zinc

Zinc is available in dietary supplements in several forms, including zinc gluconate , zinc sulfate , and zinc citrate . These forms vary in their bioavailability, with zinc gluconate and zinc citrate being better absorbed than zinc sulfate [2].

Where does zinc come from?

Zinc occurs naturally in many foods, including meat, fish, seafood, eggs, dairy products, nuts, seeds and whole grains. Oysters, beef, pumpkin seeds and lentils are particularly rich in zinc. Because plant foods tend to contain less zinc and the bioavailability of zinc from plant sources is reduced by phytates, vegetarians and vegans often have higher zinc requirements [3].

How is zinc produced?

Zinc in supplements is mostly produced synthetically by combining it with various compounds such as gluconate or citrate to increase bioavailability. These forms of zinc are easily soluble and are well absorbed by the body. Zinc is also used in fortified foods such as breakfast cereals and dairy products to increase intake [4].

Health Benefits of Zinc

Zinc and the immune system

Zinc plays a central role in supporting the immune system. It promotes the production and function of white blood cells, which are necessary for fighting infections. Studies have shown that adequate zinc intake can reduce the duration and severity of colds, especially when zinc is taken at the first signs of a cold. People who are zinc deficient are more susceptible to infections because their immune systems are weakened [5].

Zinc and Skin Health

Zinc is especially important for skin health because it promotes wound healing and protects the skin from infections. It is often used in topical creams to treat skin conditions such as acne and eczema. Zinc helps reduce inflammation and supports collagen production, which helps heal skin injuries. It also regulates sebum production, which may help prevent acne [6].

Zinc and wound healing

Zinc plays a crucial role in wound healing by supporting cell division and collagen formation. People with zinc deficiency heal more slowly and are at higher risk of skin infections. Zinc is often used in creams and ointments to treat skin wounds and ulcers because it speeds up tissue regeneration and reduces the risk of infection [7].

Zinc and Metabolism

Zinc is necessary for the activity of many enzymes that regulate carbohydrate, fat and protein metabolism. It also supports insulin production and helps stabilize blood sugar levels. People with zinc deficiency often have a disturbed metabolism, which can lead to fatigue, poor wound healing and a weaker immune system. Zinc is also involved in the synthesis of DNA and proteins, which are necessary for cell growth and repair [8].

Zinc and Fertility

Zinc is also important for fertility in both men and women. In men, zinc contributes to sperm production and quality and has a positive effect on testosterone levels. Zinc deficiency can reduce sperm quality and lead to infertility. In women, zinc plays a role in regulating the menstrual cycle and supporting egg maturation [9].

Zinc and Brain Function

Zinc contributes to cognitive function and the protection of neurons in the brain. It helps support synaptic plasticity, which is crucial for learning and memory processes. Zinc deficiency has been linked to poorer cognitive performance and an increased risk of neurodegenerative diseases such as Alzheimer's. Zinc also plays a role in regulating mood and may help alleviate depression [10].

How does zinc work in the body?

Zinc acts as a coenzyme for many enzymes involved in cell division, protein synthesis and immune defense. It supports the immune system by increasing the activity of immune cells and regulating pro-inflammatory reactions in the body. Zinc is also necessary for maintaining the integrity of cell membranes and acts as an antioxidant that protects cells from oxidative stress. In addition, zinc plays an important role in wound healing and maintaining skin health [11].

Recommended dosage and use of zinc

What is the recommended dosage?

The recommended daily allowance (RDA) of zinc is about 11 mg per day for adult men and 8 mg per day for women. Pregnant and breastfeeding women have slightly increased needs. When taking zinc to support the immune system or treat zinc deficiency, higher dosages may be needed, typically up to 40 mg per day, depending on a doctor's recommendation. It is important not to exceed the recommended upper limit of 40 mg per day to avoid side effects [12].

When should you take zinc?

Zinc can be taken at any time of the day, preferably with a meal to avoid stomach upset. It is important not to take zinc on an empty stomach as this can cause nausea. Zinc supplements are available in a variety of forms, including tablets, capsules and lozenges. When taken to treat colds, it is recommended to take zinc within 24 hours of the onset of symptoms [13].

Side effects and safety of zinc

Is zinc safe?

Zinc is safe and well tolerated in recommended doses. However, excessive intake, especially long-term high doses (over 40 mg per day), may cause side effects, including nausea, diarrhea, and headaches. Chronic zinc overdose may lead to copper deficiency, as zinc can inhibit the absorption of copper in the body. It is recommended to take zinc only in recommended doses and to consult a doctor if in doubt [14].

What are the side effects of zinc?

The most common side effects of zinc supplements include stomach upset, nausea and digestive problems, especially when taken on an empty stomach. In rare cases, zinc overdose can lead to more serious side effects such as a weakened immune system and copper deficiency. Long-term high doses of zinc can also increase the risk of cardiovascular disease as they can disrupt the balance of minerals in the body [15].

Zinc compared to other trace elements

Zinc vs. Magnesium

Both zinc and magnesium are important minerals involved in numerous biological processes. While zinc plays a key role in the immune system and wound healing, magnesium supports muscle function, energy metabolism and nerve activity. Both minerals are essential and complement each other in their functions. It is important to maintain a balanced ratio of these two minerals as they work together to contribute to overall health [16].

Zinc vs. Iron

Zinc and iron are two essential trace minerals that are crucial for the immune system and oxygen transport in the body. While zinc mainly supports immune function and wound healing, iron is necessary for the formation of hemoglobin, which carries oxygen in the blood. Both minerals are important for health, but excessive intake of one of these minerals can interfere with the absorption of the other, so a balanced ratio is important [17].

Natural Sources of Zinc

Zinc is found in many foods, including meat, seafood, nuts, seeds, and legumes. The best natural sources include oysters, beef, pork, lentils, pumpkin seeds, and chickpeas. Since plant-based foods contain less bioavailable zinc, vegetarians and vegans should make sure to consume enough zinc-rich foods or consider zinc supplements [18].

Zinc in dietary supplements

Zinc supplements are available in several forms, including zinc gluconate, zinc citrate, and zinc sulfate. Zinc gluconate and zinc citrate are considered more bioavailable and are more easily absorbed by the body than zinc sulfate. Zinc supplements are often used to support the immune system, treat zinc deficiency, or promote wound healing. It is important to follow the recommended dosage to avoid side effects [19].

Final Thoughts on Zinc

Zinc is an essential trace mineral that plays a key role in the immune system, skin health, wound healing and metabolism. It supports cell division and tissue repair and helps maintain a healthy immune system. For people looking to improve their skin health, strengthen their immune system or promote wound healing, zinc is an important supplement that can be obtained either through diet or supplements.

references

[1] Examine.com. Zinc. Available at: https://examine.com/supplements/zinc/
[2] WebMD. Zinc - Uses and Benefits. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-982/zinc
[3] Healthline. Zinc: Benefits, Uses, and Side Effects. Available at: https://www.healthline.com/nutrition/zinc
[4] Examine.com. Zinc Forms and Bioavailability. Available at: https://examine.com/supplements/zinc/
[5] Mayo Clinic. Zinc for Immune Health. Available at: https://www.mayoclinic.org/drugs-supplements-zinc/art-20366112
[6] National Institutes of Health. Zinc and Skin Health. Available at: https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/
[7] Examine.com. Zinc and Wound Healing. Available at: https://examine.com/supplements/zinc/
[8] Healthline. Zinc and Metabolism. Available at: https://www.healthline.com/nutrition/zinc-benefits
[9] Examine.com. Zinc and Fertility. Available at: https://examine.com/supplements/zinc/
[10] Examine.com. Zinc and Brain Function. Available at: https://examine.com/supplements/zinc/
[11] WebMD. Zinc in the body. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-982/zinc
[12] Healthline. Zinc Dosage and Usage. Available at: https://www.healthline.com/nutrition/zinc-dosage
[13] Mayo Clinic. Zinc Supplements and Timing. Available at: https://www.mayoclinic.org/drugs-supplements-zinc/art-20366112
[14] WebMD. Zinc Safety and Side Effects. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-982/zinc
[15] Healthline. Zinc side effects. Available at: https://www.healthline.com/nutrition/zinc-side-effects
[16] Examine.com. Zinc vs Magnesium. Available at: https://examine.com/supplements/magnesium/
[17] Examine.com. Zinc vs Iron. Available at: https://examine.com/supplements/iron/
[18] National Institutes of Health. Natural Sources of Zinc. Available at: https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/
[19] Healthline. Zinc Supplements Benefits. Available at: https://www.healthline.com/nutrition/zinc

4o