Scientifically tested: Stanford neurobiologist Andrew Huberman's supplement stack for focus, sleep, and brain performance

Neuroscientist Andrew Huberman (Stanford University) has developed a supplement stack based on studies and self-experiments for better cognitive performance, better nerves and recovery

12.05.2025, by URVI

Do you want to be wide awake during the day, switch off effortlessly in the evening and do something good for your brain in the long run?

The Huberman supplement stack offers a precise set of tools: During the day, certain amino acids and choline sources increase concentration, while in the evening, minerals, plant substances, and a special amino acid ensure deep sleep.

Everything is based on scientific studies, not advertising claims. Below, you'll learn how the individual components work, how to combine them—and what you should pay attention to so that benefits and safety go hand in hand.

Who is Prof. Andrew Huberman?

Andrew D. Huberman is a professor of neurobiology at the Stanford School of Medicine.

His institute investigates how eyes, brain and body process stress, how nerve connections are reformed and how sleep supports these processes.

He became known through the “Huberman Lab Podcast,” in which he translates research into recommendations suitable for everyday use – including the neuro-supplement stack described here.

Prof. Huberman's Neuro-Supplements at a glance
Supplement Hauptwirkung laut Literatur* Typische Dosis Tageszeit
Omega-3 (EPA/DHA) DHA trägt zur normalen Gehirnfunktion bei¹ ≥ 1 g EPA (+ DHA) Morgens
L-Tyrosin Dopamin-Vorstufe, erhält Arbeitsgedächtnis⁶ 0,5 – 2 g Vor „Deep Work“
Alpha-GPC Mehr Acetylcholin 300 – 600 mg Vor „Deep Work“
L-Theanin Gleicht negative Koffein-Spitzen aus, kann Schlaf verbessern⁴⁵ 200 – 400 mg Kaffee-Timing / Abend
Magnesium-L-Threonat Trägt zur normalen Nervenfunktion bei¹; RCT zeigt tieferen Schlaf³ 1 – 2 g 1 h vor Schlaf
Apigenin Mild anxiolytisch – verkürzt Einschlafzeit⁹ 50 – 100 mg 30 min vor Schlaf
Myo-Inositol Längere Gesamtschlafdauer⁸ 1 – 2 g 30 min vor Schlaf

Why Neuro Supplements?

A healthy brain needs three things: 1) nutrients for cell growth , 2) energy and 3) recovery .

1. Cell structure: DHA from Omega-3 keeps cell membranes supple and supports memory and concentration [1] .

2. Energy: L-tyrosine replenishes dopamine [2] ; alpha-GPC provides choline for lightning-fast signal transmission [7] .

3. Recovery: Magnesium L-threonate prolongs deep and REM sleep [3] , L-theanine calms pulse and thoughts [4,5] .

The hidden champion of neurodoping - L-Theanine

The amino acid from green tea crosses the blood-brain barrier and influences glutamate and GABA receptors.

The result: less sensory overload, more serenity. A systematic meta-study from 2024 reported significantly lower anxiety levels, better sleep onset, and no significant side effects [5] .

Neuro Support*

99% pure, decaffeinated L-theanine

With vitamin B1, B6 and glycine

*For better nerves with B1 and B6

Order now

30-day money-back guarantee

How Andrew Huberman uses the supplements in everyday life

Morning routine

1. Omega-3: ≥ 1 g

2. L-Tyrosine: 0.5 – 2 g

3. Alpha-GPC: 300 – 600 mg

4. L-Theanine: 200 – 300 mg

Focus Booster – Coffee + L-Theanine

90 minutes after waking up, Huberman drinks his coffee (75 mg caffeine) and adds 200 mg of L-theanine. Studies show that L-theanine reduces blood pressure spikes and increases alpha wave activity in the brain [4] .

Evening routine

One hour before going to bed, Huberman recommends the following:

1. Magnesium L-Threonate: 1 – 2 g
2. L-Theanine: 200 – 300 mg
3. Apigenin: 50 mg
4. Myo-Inositol: 1 g

Neuro Support*

99% pure, decaffeinated L-theanine

With vitamin B1, B6 and glycine

*For better nerves with B1 and B6

Order now

30-day money-back guarantee

Sources

1. EU Regulation 432/2012: List of permitted health claims (DHA & Magnesium).
2. Amini M. et al. (2025). Effects of vitamins and PUFA on cognitive function: meta-analysis.
3. Hausenblas H. et al. (2024). Magnesium-L-Threonate improves sleep quality: RCT.
4. Shi Y et al. (2025). L-Theanine & sleep quality in adults: RCT.
5. Zhang X et al. (2024). L-Theanine for anxiety and sleep: Systematic Review.
6. van Dalfsen J. et al. (2019). Tyrosine preserves working memory under load: RCT.
7. Eckerson J et al. (2024). Alpha-GPC acutely boosts Stroop performance: RCT.
8. Ghafar A. et al. (2020). Myo-Inositol extends total sleep time in pregnancy: RCT.
9. Yang G et al. (2023). Apigenin at the intersection of sleep & aging: Review.
10. Ventola C. et al. (2021). Alpha-GPC elevates TMAO and atherosclerosis markers: Preclinical.
11. EU Regulation 2016/1411: Caffeine claim “contributes to increased alertness” (≥ 75 mg).